Academica Weekly: The Primary Record for the Week Ending 26 July 2026
Trial registrations, clearances, recalls, guidance, safety reports, device listings, and insider filings — assembled from the primary sources with no editor in the loop.
The week of 20 July 2026 to 26 July 2026: 51 Phase 3 trial registrations; 101 Phase 2 trial registrations; 26 recall events; 100 510(k) clearances; 1 FDA guidance documents; 224 new Health Canada device licences; 3,677 ARTG device entries; 747 open-market insider purchases.
Source Ledger
The latest event date each source holds, measured against its expected publication cadence. A stale source keeps its ledger line and loses its section.
| Source | Latest event | State |
|---|---|---|
| ClinicalTrials.govPhase 1 · Phase 2 · Phase 3 · Phase 4 | 31 July 2026 | Current |
| FDA 510(k) | 17 July 2026 | Current |
| FDA PMA | 17 July 2026 | Current |
| FDA recalls | 29 July 2026 | Current |
| FDA guidance | 31 July 2026 | Current |
| FAERS | 30 June 2026 | Current |
| MAUDE | 30 June 2026 | Current |
| GUDID | 22 April 2026 | 95 days behind |
| TGA ARTG | 1 August 2026 | Current |
| Health Canada | 31 July 2026 | Current |
| FDA drug labels | 26 July 2026 | Current |
| NPPES | 11 July 2026 | Current |
| Open Payments | 31 December 2024 | 572 days behind |
| USPTO | 10 February 2026 | 166 days behind |
| PubMed | 2 August 2026 | Current |
| SEC Form 4 | 31 July 2026 | Current |
Phase 1 Trials
72 Phase 1 registrations this week; the 10 below lead the list.
| NCT | Study | Sponsor | Enrollment | Posted |
|---|---|---|---|---|
| Domatinostat With Sirolimus for Relapsed, Refractory Sarcoma and Osteosarcoma | H. Lee Moffitt Cancer Center and Research Institute | 74 | ||
| A Phase 1, Double-blind, Randomized Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of Single Dose and Multiple Doses of CG-0416 in Healthy Parti | HongKong Curegene Innovation Co., Limited | 64 | ||
| Study to Compare the Plasma Concentration of Belumosudil Given as an Oral Suspension and as a Tablet to Healthy Adult Male Participants | Sanofi | 58 | ||
| The Anesthetic and Analgesic Effect of Adjunct Liposomal Bupivacaine in Periodontal Surgical Procedures | The University of Texas Health Science Center at San Antonio | 58 | ||
| A Study to Learn How the Study Medicine Called PF-08653945 is Taken up Into the Blood in Adults With Overweight or Obesity | Pfizer | 57 | ||
| Study to Evaluate the Safety and Effectiveness of Withaferin A as a Treatment to Prevent GvHD in Transplant Patients | Tata Memorial Centre | 54 | ||
| Phase 1, First in Human (FIH), Open-Label, Single-Arm, Ascending Dose Study to Assess the Safety, Tolerability and Preliminary Immunogenicity of ITI-9001 in Japanese Patients With | Immunomic Therapeutics, Inc. | 45 | ||
| SHR2554 Plus Liposomal Mitoxantrone as First-line Treatment for Peripheral T-cell Lymphoma (PTCL) | Institute of Hematology & Blood Diseases Hospital, China | 44 | ||
| Venetoclax in Association With 3+7 and Midostaurin in FLT3-mutated Acute Myeloid Leukemia | University Hospital, Bordeaux | 41 | ||
| Study of ECC4703 With Sulfasalazine and Pitavastatin | Eccogene | 40 |
Phase 2 Trials
101 Phase 2 registrations this week; the 10 below lead the list.
| NCT | Study | Sponsor | Enrollment | Posted |
|---|---|---|---|---|
| Domatinostat With Sirolimus for Relapsed, Refractory Sarcoma and Osteosarcoma | H. Lee Moffitt Cancer Center and Research Institute | 74 | ||
| A Randomized Clinical Trial Evaluating the Efficacy of Clinical Pharmacist Assistance Along With Pharmaceutical and Non-pharmaceutical Therapy in the Early Rheumatoid Arthritis | Deraya University | 70 | ||
| SMP-656 for HER2-Positive Advanced Breast Cancer | Chengdu SciMount Pharmatech Co., Ltd. | 60 | ||
| The Anesthetic and Analgesic Effect of Adjunct Liposomal Bupivacaine in Periodontal Surgical Procedures | The University of Texas Health Science Center at San Antonio | 58 | ||
| Fosrolapitant Combined With Palonosetron to Prevent Trastuzumab Rezetecan Related CINV | Tianjin Medical University Cancer Institute and Hospital | 56 | ||
| Study to Evaluate the Safety and Effectiveness of Withaferin A as a Treatment to Prevent GvHD in Transplant Patients | Tata Memorial Centre | 54 | ||
| Fruquintinib Plus Anti-EGFR Antibody for Third-Line Treatment of RAS Wild-Type mCRC | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 46 | ||
| SHR2554 Plus Liposomal Mitoxantrone as First-line Treatment for Peripheral T-cell Lymphoma (PTCL) | Institute of Hematology & Blood Diseases Hospital, China | 44 | ||
| Venetoclax in Association With 3+7 and Midostaurin in FLT3-mutated Acute Myeloid Leukemia | University Hospital, Bordeaux | 41 | ||
| A Study of 24 to 52 Weeks Treatment to Evaluate The Efficacy And Safety of Galvokimig in Study Participants With Moderate-to-Severe Chronic Obstructive Pulmonary Disease (COPD) Wit | UCB Biopharma SRL | 402 |
Phase 3 Trials
51 Phase 3 registrations this week; the 10 below lead the list.
| NCT | Study | Sponsor | Enrollment | Posted |
|---|---|---|---|---|
| A Randomized Clinical Trial Evaluating the Efficacy of Clinical Pharmacist Assistance Along With Pharmaceutical and Non-pharmaceutical Therapy in the Early Rheumatoid Arthritis | Deraya University | 70 | ||
| A Clinical Trial of TQH3906 Capsules in Adult Patients With Moderate to Severe Plaque Psoriasis | Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd. | 400 | ||
| Safety and Efficacy of OTL78 (Zopocianine) | Clinton Bahler | 36 | ||
| Clinical Efficacy and Safety of MB LuxuryⓇ Product Containing Epigallocathecin Gallate (EGCG) on Erythema, Melanin, and Skin Hydration | Naniek Widyaningrum | 300 | ||
| Testing the Addition of a New Anti-Cancer Drug, Glofitamab to Usual Chemotherapy for Burkitt and Double Hit Lymphoma | National Cancer Institute (NCI) | 271 | ||
| Efficacy of Lipoic Acid on Chronic Ischemic Heart Failure Patients | Shanghai Zhongshan Hospital | 1,526 | ||
| Phase IIb Clinical Trial to Evaluate the Efficacy and Safety of VG081821AC Tablets in Patients With Early to Mid-stage Parkinson's Disease | Zhejiang Vimgreen Pharmaceuticals, Ltd. | 152 | ||
| Apixaban to Prevent Decompensation of Early Liver Cirrhosis Trial | University College, London | 1,142 | ||
| Y-6 Sublingual Tablets for Acute Penetrating Artery Infarction | Neurodawn Pharmaceutical Co., Ltd. | 944 | ||
| A Study to Investigate Pharmacokinetics, Safety, and Tolerability of B2227 Extended-Release Injectable Suspension and Vraylar® in Participants With Schizophrenia | Bostal Drug Delivery Co., Ltd | 84 |
Phase 4 Trials
34 Phase 4 registrations this week; the 10 below lead the list.
| NCT | Study | Sponsor | Enrollment | Posted |
|---|---|---|---|---|
| Efficacy of Intrathecal Administration of Budesonide to Prevent Bronchopulmonary Dysplasia | Indonesia University | 86 | ||
| Split Face Study of the Duration of Local Anesthetics - Fifth Arm | Weill Medical College of Cornell University | 50 | ||
| How Healthy Adults Respond to the Nasal Flu Vaccine | University of Alabama at Birmingham | 20 | ||
| An Open Label Trial to Evaluate Efficacy and Safety of Roflumilast 0.3% Cream for Chronic Plaque and Nail Psoriasis | Modern Research Associates, PLLC | 15 | ||
| SMILE Surgery in One Eye Compared to Ray Tracing-guided LASIK Surgery in the Fellow Eye | Stanford University | 62 | ||
| Omega-3-Based Nutraceutical Supplementation as Adjunctive Therapy in Adults With Otitis Media With Effusion: A Multicenter, Double-Blind, Randomized Placebo-Controlled Trial | Isola Tiberina - Gemelli Isola Hospital, Rome, Italy | 501 | ||
| The Association Between Bilateral Intermediate Cervical Plexus Block and Salivary Biomarkers of Surgical Stress Response Following Total Thyroidectomy | University Hospital Dubrava | 48 | ||
| Efficacy of Nebulized Long-Acting Bronchodilators (Formoterol and Revefenacin) vs. Short-Acting Bronchodilators (Albuterol and Ipratropium) in Patients Presenting to the Emergency | University of Tennessee Graduate School of Medicine | 280 | ||
| A Single Center, Open-Label Study to Evaluate the Ability of the TearScience™ LipiView™ II Ocular Surface Interferometer and the Keratograph® 5M to Detect Tear Film Stability | The Eye Care Institute | 20 | ||
| Iodine Drapes Used in TSA | Tnicholson | 128 |
510(k) Clearances
100 510(k) clearances this week; the 10 below lead the list.
| K number | Device | Applicant | Class | Decision |
|---|---|---|---|---|
| Catalyft PL Expandable Interbody System | Medtronic Sofamor Danek USA, Inc. | 2 | ||
| Zeiss Clinic 360 | Carl Zeiss Meditec, AG | 2 | ||
| Drivewire 35 Guidewire | Rapid Medical Ltd. | 2 | ||
| Cubresa BrainPET | Cubresa, Inc. | 2 | ||
| SportSuite Vision Software | Stryker Endoscopy | |||
| Diode laser hair removal machine (QDTM-04) | Beijing Nubway S&T Co., Ltd. | 2 | ||
| Tritanium® C Anterior Cervical Cage; Tritanium® PL Cage; Tritanium® TL Curved Posterior Lumbar Cage; Aero® -C Cervical Cage System; AVS® Anchor-C Cervical | Stryker Spine | 2 | ||
| Dental Zirconia Blank & Coloring Liquid | Hunan Qinghao Puzhong Technology Co., Ltd. | 2 | ||
| Natural Cycles | Natural Cycles Nordic AB | 2 | ||
| BIOFIRE® FILMARRAY® Tropical Fever Panel Control Kit | Biofire Defense, LLC | 2 |
PMA Approvals
284 PMA decisions this week; the 10 below lead the list.
| PMA | Device | Applicant | Decision |
|---|---|---|---|
| Edwards Crimper: 9600CR | Edwards Lifesciences, LLC | ||
| Spinal Cord Stimulation (SCS) Implantable Pulse Generator (IPG) | Abbott Medical | ||
| Edwards SAPIEN 3 Pulmonic Delivery System: 9630PL29 | Edwards Lifesciences, LLC | ||
| Deep Brain Stimulation (DBS) Implantable Pulse Generator (IPG) | Abbott Medical | ||
| HeartMate 3 Left Ventricular Assist System (LVAS) | Abbott Medical | ||
| Percepta Bipolar CRT-P, Percepta Quadripolar CRT-P, Serena Bipolar CRT-P, Serena Quadripolar CRT-P, Solara Bipolar CRT-P | Medtronic, Inc. | ||
| AED 3; CPR Uni-Padz | ZOLL Medical Corporation | ||
| Amplia MRI CRT-D, Amplia MRI Quad CRT-D, Brava CRT-D, Brava Quad CRT-D, Claria MRI CRT-D, Claria MRI Quad CRT-D, Cobalt | Medtronic Cardiac Rhythm Disease Management | ||
| Evera S DR ICD, Evera S VR ICD, Evera XT VR ICD, Mirro MRI DR ICD, Mirro MRI VR ICD, Primo MRI DR ICD, Primo MRI VR ICD, | Medtronic Cardiac Rhythm Disease Management | ||
| Vercise Deep Brain Stimulation (DBS) Systems | Boston Scientific Corp |
Recalls
26 recall events this week; the 10 below lead the list.
| Firm | Product | Reason | Catalog rows | Posted |
|---|---|---|---|---|
| Windstone Medical Packaging, Inc. | AMS ALIGNED MEDICAL SOLUTIONS medical convenience kits labeled as: 1) Laminectomy Pack, Pack Number AMS13574A; 2) ACDF/Fusion Pack, Pack Number AMS14710B; 3) Spine Pack, Pack Number AMS14991A; 4) | The recall notice was initiated due to a Medicom Urgent Medical Device Recall. Medicom is recalling specific lots of Ritmed Neurological Sponges Non-Sterile Models 55992C to 55998C due to potential for unexpected variability of endotoxin le | 4 | |
| Permobil Inc | M5 Corpus Power Wheelchair REF,120032 | This recall is being reported retroactively. Power Platform firmware is missing specific drive inhibit logic. This issue may allow the chair to drive under restricted conditions, and may create an unstable condition in certain circumstances | 1 | |
| Argon Medical Devices, Inc | L-Cath Midline S/L Catheter 20ga (3F) 1mm x 20cm, REF: 384620 | Catheters, indicated for short/long-term peripheral access to central venous system for the administration of fluids, medications, nutrients; and sampling, may experience leaking and/or cracking at the hub, which may lead to replacement, in | 2 | |
| Permobil Inc | Permobil M3 Corpus Power Wheelchair with Heavy Duty Shock REF:120031, Model version 3 | This recall has been reported retroactively. The power wheelchair firmware lacks a speed restriction to maintain stability when the seat lift exceeds 50 mm, which may cause the user to fall from the wheelchair or the wheelchair to tip over, | 1 | |
| Alphatec Spine, Inc. | SafeOp Patient Interface, REF: AIX11240, part of SafeOp 3: Neural Informatix System | Intraoperative neuromonitoring device, due to a software issue, may experience loss or interruption of triggered electromyography (tEMG) functionality during use, displaying as system faults, loss of communication between the Patient Interf | 1 | |
| Karl Storz Endoscopy | Flexible Hystero-Fiberscope Kits REF: 11264BBU1, 11264BBUK1, that contain expired Single Use Endoscopic Seal: GYN, REF: 26153EAU/1. | Flexible hysteroscopes indicated for use during diagnostic and operative hysteroscopic procedures may contain an expired single use endoscopic seal for gynecology use, which could impact the assurance of sterility. | 1 | |
| Medline Industries, LP | Medline medical convenience kits labeled as: NEURO PACK, Medline Kit SKU DYNJ59397P | Medline Industries, LP is issuing a recall for specific Medline convenience kits containing BD PurPrep 26 mL which may be contaminated with low levels of Bacillus species. | 4 | |
| Medline Industries, LP | MEDLINE medical procedure convenience kit labeled as: HIP CDS-LF, Medline kit SKU CDS984556N | The procedure kits contain ICU Medical, Inc. pain management kits containing Bupivacaine Hydrochloride in Dextrose Injection, USP, which were recalled due to quality issues that could result in drug ineffectiveness. | 2 | |
| Medtronic MiniMed, Inc. | MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android) | For MiniMed Go app version 1.0.0 and 1.1.0, when the Set day and night is turned OFF and missed dose or Correct high glucose alerts are enabled, the associated alerts will not be triggered during the nighttime. This could result in mi | 1 | |
| Medline Industries, LP | Medline convenience kits containing Bard Silastic Foley Catheters (French sizes 16, 18, 20) 5cc balloons. UROLOGY ROBOTIC PROCEDURE PACK DYNJ0945779U | Affected kits contain recalled Bard Silastic Foley Catheters. Catheters were recalled by manufacturer due to increased amount of raw material present on the surface of the catheter. Issue may result in the use of urinary catheters that exhi | 9 |
FDA Guidance
1 guidance documents this week.
| Title | Topic | Issued |
|---|---|---|
| Hemodialysis Blood Tubing Sets - Premarket Notification (510(k)) Submissions: Guidance for Industry and Food and Drug Administration Staff | Premarket, 510(k), Gastroenterology-Urology; Medical Devices; Center for Devices and Radiological Health; Final |
Drug Safety Reports (FAERS)
352,949 adverse event reports this week; the 10 below lead the list.
| Reaction | Reports |
|---|---|
| Off label use | 19,437 |
| Drug ineffective | 17,826 |
| Nausea | 13,583 |
| Product dose omission issue | 12,230 |
| Diarrhoea | 12,101 |
| Death | 11,969 |
| Fatigue | 11,899 |
| Pruritus | 10,348 |
| Headache | 9,032 |
| Meningioma | 8,392 |
Device Safety Reports (MAUDE)
333,226 device event reports this week; the 10 below lead the list.
| Brand | Manufacturer | Events |
|---|---|---|
| FreeStyle Libre 3 | 26,773 | |
| Dexcom G7 Continuous Glucose Monitoring System | 16,748 | |
| FreeStyle Libre 3 Plus | 13,218 | |
| t:slim X2 Insulin Pump with Control-IQ Technology | 10,423 | |
| DreamStation Auto CPAP | 8,072 | |
| CareLink SmartSync Common App iOS | 7,354 | |
| Inset Guard | 7,073 | |
| t:slim X2 Insulin Pump with Control-IQ+ Technology | 5,375 | |
| Quick Set | 4,518 | |
| MiniMed 780G US System BLE Connect 3.0 mg/dL | 4,366 |
Device Listings (GUDID)
27,811 device listings this week; the 10 below lead the list.
| Brand | Company | GMDN | Published |
|---|---|---|---|
| Melpex | Melpex Beauty Instruments | General-purpose surgical scissors, reusable | |
| Anyplus Peek Cage System | GS Medical Co., Ltd. | Polymeric spinal interbody fusion cage | |
| Wrap Around Quick Release | Shielding International Inc. | Radiation shielding apron | |
| Anyplus Peek Cage System | GS Medical Co., Ltd. | Polymeric spinal interbody fusion cage | |
| ProCure | Twin Med, LLC | Wound hydrogel dressing, non-antimicrobial | |
| TrellOss®-MCP | Nexxt Spine, LLC | General internal orthopaedic fixation system implantation kit | |
| Golden Isles Pedicle Screw System | Intelivation, LLC | Orthopaedic implantation sleeve, reusable | |
| TrellOss®-MCP | Nexxt Spine, LLC | Spinal fixation plate, non-bioabsorbable | |
| K2-HF SHOULDER, SH-6 T powder, 20g. | Yeti Dentalprodukte GmbH | Dental appliance fabrication material, ceramic | |
| Wrap Around Quick Release | Shielding International Inc. | Radiation shielding apron |
Australia (TGA ARTG)
3,677 ARTG device entries this week; the 10 below lead the list.
| Brand | Manufacturer | Sponsor | Class | Effective |
|---|---|---|---|---|
| myray | Cefla SC | William Green Pty Ltd | Class IIb | |
| myray | Cefla SC | William Green Pty Ltd | Class IIa | |
| myray | Cefla SC | William Green Pty Ltd | Class IIa | |
| myray | Cefla SC | William Green Pty Ltd | Class IIb | |
| myray | Cefla SC | William Green Pty Ltd | Class IIa | |
| myray | Cefla SC | William Green Pty Ltd | Class IIb | |
| myray | Cefla SC | William Green Pty Ltd | Class IIb | |
| myray | Cefla SC | William Green Pty Ltd | Class IIb | |
| myray | Cefla SC | William Green Pty Ltd | Class IIa | |
| myray | Cefla SC | William Green Pty Ltd | Class IIa |
Canada (Health Canada MDALL)
224 new device licences this week; the 10 below lead the list.
| Device | Company | Class | Licensed |
|---|---|---|---|
| Bd Nexiva Closed IV Catheter System - Dual Port with Bd Maxzero Needle-Free Connector | Becton Dickinson Infusion Therapy Systems Inc. | 2 | |
| Bd Nexiva Closed IV Catheter System - Dual Port - Bd Q-Syte Needle-Free Connector | Becton Dickinson Infusion Therapy Systems Inc. | 2 | |
| Charge Base | Zolar Technology & Mfg Co. Inc. | 2 | |
| Rotary Files | Zolar Technology & Mfg Co. Inc. | 2 | |
| Deep Ensemble for Recognition of Malignancy (Derm) | Skin Analytics Limited | 3 | |
| Acl Top 970 Cl | Instrumentation Laboratory Co. | 3 | |
| Idk Extract Stool Preparation System | Immundiagnostik AG | 2 | |
| Endoscopic Image Processor | Hunan Endoso Life Technology Co., Ltd. | 2 | |
| Single-Use Bronchoscope | Hunan Endoso Life Technology Co., Ltd. | 2 | |
| Headgear Frame Assembly | Shenzhen Sany Pioneer Technology Co., Ltd. | 2 |
Drug Labels
777 label effective dates this week; the 10 below lead the list.
| Brand | Generic | Manufacturer | Effective |
|---|---|---|---|
| Elevate Beard Regrowth Treatment | Beard Regrowth Treatment | Guangzhou Jianyuan Biological Technology Co.,Ltd | |
| Acolye Numbing Cream Anorectal(Hemorrhoidal) Cream | Lidocaine | Guangdong Aimu Biological Technology Co., Ltd | |
| Numbing | Lidocaine | Yiyangyuan Life Sciences (Hong Kong) Co., Limited | |
| hydrocortisone | Hydrocortisone | Eywa Pharma Inc | |
| Luxe Color Foundation | Octinoxate 7% Zinc Oxide 5% | Guangzhou Huixue Biotechnology Co., Ltd. | |
| CVS Topical Anesthetic Hemorrhoidal | Dibucaine | CVS Pharmacy, Inc. | |
| HydrOXYzine Hydrochloride | Hydroxyzine Hydrochloride | A-S Medication Solutions | |
| No7 Restore and Renew Multi Action Day Cream Sunscreen Broad Spectrum SPF 25 Kit | Avobenzone, Homosalate, Octinoxate, Octisalate, Octocrylene | Xact Packing Limited | |
| Aeroaid | Benzalkonium Chloride | Aero Healthcare US LLC | |
| escitalopram | Escitalopram | Preferred Pharmaceuticals Inc. |
Workforce (NPPES)
58,772 new provider enumerations this week; the 10 below lead the list.
| State | New providers | Organizations |
|---|---|---|
| CA | 7,952 | 1,185 |
| TX | 4,174 | 1,146 |
| FL | 3,956 | 1,137 |
| NY | 2,967 | 489 |
| MI | 2,564 | 387 |
| OH | 2,470 | 418 |
| IL | 1,973 | 385 |
| PA | 1,815 | 295 |
| MD | 1,805 | 393 |
| NC | 1,788 | 433 |
Industry Payments (Open Payments)
15,384,974 industry payments this week; the 10 below lead the list.
| Payer | Total (USD) | Payments |
|---|---|---|
| BioNTech SE | 180,558,679 | 164 |
| AbbVie Inc. | 156,382,683 | 1,720,745 |
| Stryker Corporation | 132,155,940 | 162,439 |
| Medtronic, Inc. | 117,649,217 | 342,148 |
| Arthrex, Inc. | 104,199,464 | 49,443 |
| Edge Endo LLC | 91,139,127 | 11 |
| Zimmer Biomet Holdings, Inc. | 83,904,351 | 32,760 |
| Intuitive Surgical, Inc. | 72,225,869 | 116,855 |
| Takeda Pharmaceuticals U.S.A., Inc. | 71,616,187 | 171,595 |
| Advanced Accelerator Applications | 63,931,988 | 167 |
Patents (USPTO, A61)
95 medtech patent grants this week; the 10 below lead the list.
| Assignee | Grants |
|---|---|
| Globus Medical, Inc. | 8 |
| Hytto Pte. Ltd. | 2 |
| Medicrea International | 2 |
| Koninklijke Philips N.V. | 2 |
| Warsaw Orthopedic, Inc. | 2 |
| Neodyne Biosciences, Inc. | 1 |
| GlaxoSmithKline Intellectual Property Development Limited | 1 |
| University of Florida Research Foundation, Incorporated | 1 |
| Intuitive Surgical Operations, Inc. | 1 |
| Universitätsspital Basel | 1 |
Literature (PubMed)
197,768 literature records this week; the 10 below lead the list.
| PMID | Title | Journal | Revised |
|---|---|---|---|
| Antagonism of CD95 signaling blocks butyrate induction of apoptosis in young adult mouse colonic cells. | The American journal of physiology | ||
| The extra- and intracellular barriers to lipid and adenovirus-mediated pulmonary gene transfer in native sheep airway epithelium. | Gene therapy | ||
| Unique lipoproteins secreted by primary astrocytes from wild type, apoE (-/-), and human apoE transgenic mice. | The Journal of biological chemistry | ||
| Deregulation of p53/p21Cip1/Waf1 pathway contributes to polyploidy and apoptosis of E1A+cHa-ras transformed cells after gamma-irradiation. | Oncogene | ||
| Development of an enzyme-labeled oligonucleotide probe for detecting the Escherichia coli attaching and effacing A gene. | Microbiology and immunology | ||
| Dynamin is required for recombinant adeno-associated virus type 2 infection. | Journal of virology | ||
| Dominance hierarchy formation in juvenile crayfish procambarus clarkii | The Journal of experimental biology | ||
| EMAN: semiautomated software for high-resolution single-particle reconstructions. | Journal of structural biology | ||
| Diverse behavioural defects caused by mutations in Caenorhabditis elegans unc-43 CaM kinase II. | Nature | ||
| Syntaxin 1A is expressed in airway epithelial cells, where it modulates CFTR Cl(-) currents. | The Journal of clinical investigation |
Literature by Subject (MeSH)
404,657 annotated literature records this week; the 10 below lead the list.
| MeSH heading | Articles |
|---|---|
| Humans | 198,188 |
| Female | 118,043 |
| Male | 108,431 |
| Animals | 62,439 |
| Middle Aged | 62,133 |
| Adult | 59,952 |
| Aged | 46,526 |
| Mice | 24,724 |
| Young Adult | 22,860 |
| Retrospective Studies | 21,381 |
Insider Buying (Form 4)
747 open-market insider purchases this week; the 10 below lead the list.
| Ticker | Owner | Traded | Shares | Value (USD) |
|---|---|---|---|---|
| NONE | Blackstone Private Multi-Asset Credit & Income Fund | 5,162,524 | 135,000,000 | |
| Lincoln Financial Investments Corp | 7,381,890 | 75,000,000 | ||
| Fairmount Funds Management LLC | 5,120,700 | 74,250,150 | ||
| NONE | UAW Chrysler Retirees Medical Benefits Plan | 56,436 | 49,499,614 | |
| NONE | Assured Guaranty Ltd. | 1,465,715 | 36,400,000 | |
| B&R Technology Sponsor LLC (Cayman) | 2,750,000 | 27,500,000 | ||
| RA Capital Management, L.P. | 919,940 | 25,094,209 | ||
| RA Capital Management, L.P. | 461,461 | 13,496,223 | ||
| Allbaugh Larry Eugene | 289,773 | 12,750,012 | ||
| Huang Jack Jiajia | 640,440 | 11,041,186 |
Academica Weekly is assembled and published automatically each week. This issue covers 20 July 2026 to 26 July 2026 and was built on 3 August 2026.